OrangeTwist combines luxury wellness care with medical-grade treatments for a highly personalized, effective approach that focuses not just on weight loss, but also includes ongoing healthy lifestyle changes for a more well-rounded, sustainable approach. Bonus: We can also help you sculpt and smooth your body after you hit your goal with CoolSculpting!

Semaglutide and Tirzepatide are FDA-approved medications that help with weight loss by working with your body’s natural systems to control hunger and improve metabolism. Semaglutide mimics a hormone called GLP-1, while Tirzepatide targets both GLP-1 and GIP hormones. Both treatments help reduce appetite, slow digestion so you feel full longer, and balance blood sugar to curb cravings, making it easier to eat less and stay satisfied.

The results vary from person to person, however when combined with healthy eating and lifestyle changes, many people using Semaglutide see steady weight loss of 1-2 pounds per week and 15-20% of their body weight over several months.

OrangeTwist is your treatment shop for all your aesthetic needs—now including Semaglutide and Tirzepatide with added glycine! Our team will guide you every step of the way, ensuring you’re fully supported throughout your entire journey. You’ll come in weekly for treatments, where we’ll answer all your questions and ensure everything is going smoothly.

You’ll also be part of our TwistOff community! TwistOff is our exclusive MWL membership that gives you additional discounts on treatments and products. Plus, you’ll have access to your very own Medical Weight Loss Concierge—your personal guide to help you stay on track and answer any questions along the way.

Most importantly, at OrangeTwist, your safety is our top priority. Our MWL program is overseen and curated by our medical physicians. Our in-center team will administer your treatment, answer your questions, and cheer you on throughout the entire journey, ensuring it’s both safe and effective. We are proud to support you through a journey that’s not only personalized but truly cared for.

Semaglutide is a peptide originally developed to manage diabetes, with weight loss effects noted since 2005. It is now FDA-approved for weight management and works by mimicking a hormone called GLP-1—and in the case of Tirzepatide, also GIP—which regulate appetite and food intake.

Essentially, these medications help you feel fuller for longer while consuming fewer calories. This reduced caloric intake supports weight loss and increases awareness of your eating habits as your body naturally adjusts to healthier portion sizes.

Both medications are typically administered once every four weeks. Semaglutide starts at 0.2 mg with incremental increases every four weeks, depending on patient sensitivity. Tirzepatide begins at a starting dose of 2.125 mg. Gradual increases help maximize effectiveness while minimizing side effects as your body adapts.

Treatment duration varies depending on your weight loss goals, tolerance, and medical guidance. Many clients reach their health and wellness goals in as little as three months. During your consultation, we’ll estimate your treatment timeline and adjust as we track your progress.

The medication is administered using a small needle into the fatty tissue. You may be asked to stay briefly after your injection to ensure no immediate reactions. Mild side effects such as nausea or temporary injection site discomfort are normal.

To prepare for your appointment, follow any medication or food restrictions provided by your healthcare provider. Certain foods and medications may interfere with the effectiveness of Semaglutide or Tirzepatide, so it’s important to follow instructions closely to ensure the best results and proper treatment management.

Blood tests help evaluate kidney function, identify potential risks, and detect any underlying conditions that may affect your response to Semaglutide or Tirzepatide, such as liver issues or interactions with other medications. This ensures the treatment is safe, appropriate, and monitored effectively. Clients must fast for 12 hours before labs—water is allowed.

Common gastrointestinal side effects may include nausea, vomiting, diarrhea, constipation, or abdominal pain. You may also experience temporary injection site soreness or redness. Some clients notice fatigue due to reduced caloric intake—monitoring your protein and macro levels can help. Headaches may also occur.

You’ll begin with either an in-center or virtual consultation, where you can openly discuss any questions or concerns. Once medically cleared, you’ll have your blood drawn (with a required 12-hour fast). After lab review, we’ll schedule your first dose with one of our providers. At checkout, we’ll schedule your next appointment—each visit bringing you closer to your weight loss goals.

Yes! You earn 50 Alle points with each injection appointment.

Yes! You can safely do CoolSculpting and/or Emsculpt/CoolTone on the same day as your treatment, and throughout your weight loss journey. We actually recommend pairing body contouring with Semaglutide for optimal results.

Do: Eat lean proteins and whole foods, drink at least 32 oz of water with electrolytes, incorporate fiber daily, and take prebiotics and probiotics.

Don’t: Consume processed foods with artificial colors or flavors, sugary beverages like soda, or alcohol. Not following these guidelines may increase the chances of feeling unwell.

Yes. Make sure to inform your surgeon and anesthesia or sedation provider that you are using Semaglutide or Tirzepatide for weight loss. You may need to pause treatment at least one week prior, depending on physician discretion. These medications slow stomach emptying, which can be dangerous during anesthesia if the stomach is not empty.