Injectables
Restylane Kysse at OrangeTwist
Lips that move like yours. Restylane Kysse is the FDA-approved hyaluronic acid lip filler designed to enhance shape, add subtle volume, and feel completely natural when you smile, kiss, or speak. Soft to the touch. Honest about the work.
About the treatment

Lips, but better. Still yours.
Lip filler that feels stiff is filler that has been done wrong. Restylane Kysse is built with a flexibility that lets the product move with your expression, not against it. The result is fuller, softer, more defined lips that look and feel like your own.
- Designed for natural movement
- FDA-approved lip enhancement
- Soft, kissable texture
What is Restylane Kysse and how does it work?
Restylane Kysse is an FDA-approved hyaluronic acid filler from Galderma, specifically designed for lip enhancement. What sets Kysse apart is XpresHAn Technology, which gives the filler flexibility and stretch. Lips move constantly when you talk, smile, kiss, and eat, and a lip filler that cannot move with that motion ends up looking and feeling artificial.
Like all hyaluronic acid fillers, Restylane Kysse adds volume directly in the layer where the body’s own hyaluronic acid has thinned, smoothing fine lines and enhancing shape in the process. Because Kysse is specifically formulated for the lips, it integrates softly into lip tissue and avoids the firm, overdone look associated with denser filler products used outside their intended area.
Restylane Kysse was the first FDA-approved lip filler designed and tested specifically for expressive natural movement, and remains one of the most clinically studied lip filler products on the market.

The OrangeTwist Difference
Every Restylane Kysse injection is carried out by a licensed provider with specific training in lip filler technique. Lip work is a specialty within injectables, and the difference between a beautifully done lip and an obvious one is the practitioner.
We are not here to overfill. Lip filler done well looks softer, not bigger. Our providers will recommend a conservative starting dose and build over time if needed.
Like all hyaluronic acid fillers, Restylane Kysse can be dissolved with hyaluronidase if you are unhappy with the result. OrangeTwist providers carry hyaluronidase on-site.
Lip filler often combines with Botox for the lip flip and is a popular pairing with cheek or jawline filler for overall facial balance. Your provider will design the right combination.
Prep 101
Your Treatment Timeline

You Review
Your provider will examine the natural shape of your lips, listen to what you want to achieve, and recommend a specific amount of Restylane Kysse for the result you want. They will walk through pricing transparently and discuss whether one syringe or a more gradual two-stage approach suits your goals.

Onboarding
Avoid blood-thinning medications like ibuprofen, aspirin, fish oil, and vitamin E for a few days before your appointment where possible. Skip alcohol for 24 hours beforehand. Avoid intensive workouts the morning of. Come in with clean lips, free of lipstick or lip products. Eat beforehand. Hydrate.

Ongoing Care
Your provider will apply topical numbing cream, sometimes combined with a dental block for clients who prefer additional comfort. Restylane Kysse also contains lidocaine, which makes the injections themselves more comfortable. The procedure takes 30 to 45 minutes. Most clients describe the sensation as spicy and contained, gone in moments.

Maintenance and Transition
Expect significant swelling for 24 to 72 hours, especially for the first day. Use cool compresses (with a clean cloth between ice and skin), sleep elevated, and avoid pressure on the treated area for 24 hours. Skip strenuous exercise, alcohol, and heat exposure for 24 to 48 hours. Avoid drinking from a straw and pursing the lips for the first day. Your provider will share specific aftercare.
Immediate, then more so.
Restylane Kysse results typically last up to a year.
Lip filler in general requires more frequent maintenance than facial filler due to the constant movement of the lips and the way the body metabolizes hyaluronic acid in this area. Most clients return for a refresh every nine to 12 months.

Frequently Asked
Questions and Answers
Restylane Kysse is an FDA-approved hyaluronic acid lip filler made by Galderma. It is specifically designed for lip enhancement and uses XpresHAn Technology, which gives the filler flexibility and stretch so it moves naturally with your expression.
Like all hyaluronic acid fillers, Kysse adds volume directly in the layer of the lip where your skin’s own hyaluronic acid has thinned. The flexibility built into the product means the filler stretches and recovers naturally as the lips move, avoiding the stiff, frozen feeling that overdone filler can produce.
XpresHAn Technology is the formulation used in several Restylane fillers, including Kysse. It gives the hyaluronic acid filler flexibility and stretch, which is particularly important for areas of high facial movement like the lips.
JUVÉDERM Volbella and Ultra are both lip-suitable products with their own profiles. Kysse and JUVÉDERM lip products are formulated differently and feel slightly different in the lips. Some clients prefer the softer feel of Volbella, others the structured plumping of Ultra, others the natural movement of Kysse. Your provider will recommend the right product based on your lip anatomy and goals.
Restylane Kysse is used for natural lip volume, definition of the lip border, refining the cupid’s bow, smoothing fine lip lines, and addressing natural lip asymmetry. Your provider will discuss what is appropriate for your specific lips at your You Review.
Yes. Kysse is a hyaluronic acid filler and can be dissolved with hyaluronidase if you are unhappy with the result. OrangeTwist providers carry hyaluronidase on-site.
Yes. Every OrangeTwist lip filler client starts with a complimentary You Review. Your provider will examine your natural lip shape, listen to your goals, and recommend the right amount of Kysse for the result you want.
Let your provider know about any history of cold sores (which can be triggered by lip filler), any medications including blood thinners, allergies, autoimmune conditions, and whether you are pregnant or breastfeeding.
Allow two weeks between lip filler and any significant event. Initial swelling can be dramatic for the first 24 to 72 hours, and the final settled result is typically clear by week two.
Pricing depends on the number of syringes used. Most clients start with one syringe of Kysse and can return for additional product if more is needed. Your provider will walk through exact pricing at your You Review.
Most lip filler appointments take 30 to 45 minutes. Allow additional time for topical numbing to take effect.
Most first-time lip filler clients start with one syringe (1ml) of Kysse. Some clients return for a second syringe a few weeks later for more substantial volume. Conservative dosing is our default.
Yes. OrangeTwist offers financing through CareCredit, Alle Cherry, and PatientFi. Ask your provider about options at your You Review.
Volume is visible immediately. Swelling masks the final outcome for the first one to two weeks. By week two, the settled result is typically clear.
Up to a year on average. Most clients return for a refresh every nine to 12 months. Lip filler in general metabolizes faster than facial filler due to the constant movement of the lips.
Not when done well. Restylane Kysse was designed specifically for natural-looking, expressive movement, and our providers use conservative dosing. The goal is fuller, softer, more defined lips that still look and feel like your own.
Yes. Kysse is a hyaluronic acid filler and can be dissolved with hyaluronidase. Most providers wait two weeks for the final result to settle before considering dissolution.
With topical numbing and the lidocaine in the product, most clients find lip filler manageable. The sensation is spicy and contained, gone in moments.
Most clients return to normal activities immediately, though expect lip swelling for the first 24 to 72 hours. Most clients are camera-ready around day five to seven.
For the first 24 to 48 hours: avoid strenuous exercise, saunas, and hot environments; do not apply pressure to or massage the lips; avoid alcohol; avoid drinking from straws; skip kissing and any pursing of the lips for the first day; hold off on facials, lasers, or any procedure on the area for two weeks.
Wait at least 24 hours before applying lipstick or any lip product. When you do, apply gently and use clean applicators.
Yes. Kysse has a strong clinical safety record. Like all FDA-approved hyaluronic acid fillers, it is well tolerated and the active ingredient is one the body produces naturally.
Kysse is generally not recommended if you are pregnant or breastfeeding, have a known allergy to hyaluronic acid or lidocaine, have an active skin infection in the treatment area, have an active cold sore outbreak, have a history of frequent cold sore outbreaks, or have certain autoimmune conditions. Always disclose your full medication and health history at your You Review.
Common side effects include swelling, bruising, redness, and tenderness at the injection sites. Lip swelling can be dramatic in the first 24 to 72 hours but settles. Rare side effects include lumps, asymmetry, cold sore reactivation, or, very rarely, vascular complications.
Lip filler does not cause cold sores, but the injection process can reactivate the virus in clients who carry it. If you have a history of cold sores, let your provider know at your You Review. They may recommend antiviral prophylaxis taken before and after treatment.
All Restylane Kysse treatments at OrangeTwist are performed by licensed medical professionals with specific training in lip filler technique, supervised by our Medical Advisory Board.
Affordable options
Flexible financing that fits your life
We believe the right treatment should be accessible when you need it, not only when it fits your budget. That’s why we offer flexible financing options that let you spread the cost over time. It’s simple, transparent, and tailored to your situation so you can focus on your results, not the payment.
Restylane Kysse
$161 / month over 6 months*
*Financing is subject to approval. Terms, interest rates, and monthly payments may vary depending on your provider and chosen plan. The example above is based on an APR of 9.9%.

The OrangeTwist Difference
You’re Glowing, We’re Blushing
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Highly Skilled Providers
True experts in their craft, our licensed providers are continuously trained in the latest techniques, treatments, and technologies.
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A Welcoming Experience
Our treatment shops are bright, modern, and welcoming, with a team that’s as approachable as they are skilled.
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A Personalized Touch
No two clients are the same — and we treat them that way. We start every journey with a full You Review so we can understand your unique goals and how to achieve them.
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