Wellness
Medical Weight Loss
Weekly GLP-1, provider-prescribed and built around your goals. Science does the heavy lifting. You do the rest.
About the treatment
A Different Kind of Weight Loss
OrangeTwist GLP-1 pairs Semaglutide or Tirzepatide with a provider who determines the right medication and dose for you. Self-administer at home, or come in-center for an additional fee.
- Provider-determined eligibility and dosing
- Sourced through licensed pharmacy partners, with consistent, verified dosing
- Weekly injection, self-administered at home or in-center
What is Medical Weight Loss and How Does it Work?
OrangeTwist gives eligible clients access to Semaglutide and Tirzepatide, the two GLP-1 receptor agonists that have changed the landscape of weight management over the past five years.
GLP-1 medications work with the body’s natural appetite and satiety signaling. They slow gastric emptying, reduce cravings, and increase the feeling of fullness after eating. The result is a sustainable reduction in caloric intake without the constant willpower load that traditional dieting demands.
OrangeTwist offers Semaglutide, the active ingredient in Ozempic and Wegovy, and Tirzepatide, the active ingredient in Mounjaro and Zepbound. Your provider may recommend baseline lab work before prescribing your medication and starting dose at your You Review. Both medications are given as a once-weekly injection, self-administered at home or in-center for an additional fee.
Science guided
Medical Weight Loss Options
Every OrangeTwist GLP-1 client starts from the same place a YouReview. From there, it’s about which medication fits your goals and clinical profile.
Semaglutide
The established option. The active ingredient in Ozempic and Wegovy, with the longest clinical track record in the weight-management category.
- GLP-1 receptor agonist
- Once-weekly injection, self-administered at home or in-center (fee applies)
- Sourced through licensed pharmacy partners
A proven starting point for Medical Weight Loss
Tirzepatide
The active ingredient in Mounjaro and Zepbound. A dual GIP and GLP-1 receptor agonist, newer to the category with a growing evidence base.
- Dual GIP and GLP-1 receptor agonist
- Once-weekly injection, self-administered at home or in-center (fee applies)
- Sourced through licensed pharmacy partners
A good option for those who have plateaued on semaglutide
Compliment your Medical Weight Loss journey
Related Concerns
Jawline Definition Treatment
A jawline can blur from fat, from softening skin, or from lost structure.
Skin Laxity Treatment
The gradual loss of firmness as collagen and elastin slow, most visible along the jaw, neck, and lower face.
Stubborn Fat Treatment
The pockets that hang on no matter how consistent you are with food and training.
The TwistOff Difference
There are plenty of places to get GLP-1 medication. Fewer that get it right. Here’s what the OrangeTwist Difference looks like for Medical Weight Loss.
Compounded versions of GLP-1 medications can be cheaper, but quality and consistency vary widely. OrangeTwist sources medication through licensed pharmacy partners, with consistent, verified dosing every time.
Bright, welcoming, and run by people who care about you as a whole client, not just a number on the scale. Licensed providers are here to guide you on the best treatment plan, administer injections and order lab work.
No membership required for Medical Weight Loss, though membership is the best value. Add TwistUp or TwistUp+ for Beauty Bank credit and a treatment discount, applied across the menu, including your GLP-1 medication.
Once you’ve reached your goals, OrangeTwist is your one-stop treatment shop for what comes next: CoolSculpting Elite for stubborn fat pockets that don’t respond to diet and exercise, and skin-tightening treatments like ZenTite and Density for skin left loose after weight loss.
Prep 101
Your Treatment Timeline
Who it’s for
OrangeTwist GLP-1 is for eligible clients working toward meaningful, medically grounded weight loss. Eligibility is determined by your provider based on your BMI, weight history, current medications, and overall health profile at your You Review.
What to expect
Your provider confirms your eligibility and may recommend lab work (a separate cost) before prescribing the medication and starting dose that fits your profile at your You Review.
From there, you can self-administer a once-weekly subcutaneous injection at home, or come in-office for an additional fee. Common early side effects include nausea, mild gastrointestinal upset, and changes in appetite, which typically ease as your body adjusts.
Your results
Most clients begin noticing changes in appetite and eating patterns within the first weeks, with visible weight loss typically starting within the first one to three months. Individual results vary based on starting weight, medication, lifestyle, and clinical profile. Your provider will set realistic, evidence-based expectations at your You Review.
Ready to lose weight on your terms?
Book your complimentary, no-pressure You Review and let’s talk about what Medical Weight Loss at OrangeTwist can do for you.
Frequently Asked
Questions and Answers
OrangeTwist Medical Weight Loss gives eligible clients access to Semaglutide or Tirzepatide, given as a once-weekly injection. Self-administer at home, or come in-center for an additional fee. Your provider determines eligibility, medication, and dose at your You Review.
Semaglutide is the GLP-1 medication with the longest clinical track record. Tirzepatide is a dual GIP and GLP-1 agonist that is newer to the category, with a growing evidence base. Your provider will recommend the right option based on your clinical profile and goals at your You Review.
GLP-1 receptor agonists are a class of medications originally developed for type 2 diabetes that have since been approved for chronic weight management in eligible clients. They work with the body’s natural appetite signaling, slowing gastric emptying and reducing cravings.
Ozempic and Wegovy are brand names for Semaglutide. Mounjaro and Zepbound are brand names for Tirzepatide. OrangeTwist provides these same active ingredients through licensed pharmacy partners, prescribed by a provider at your You Review.
Yes. OrangeTwist GLP-1 is a prescription medication. Eligibility is determined by a licensed provider at your You Review based on your health history, current medications, and clinical profile.
Yes. Every client starts with a provider-led You Review. Your provider will assess your eligibility, discuss your health history and goals, and recommend the right medication if you qualify.
Eligibility is determined by a licensed provider based on clinical criteria, including your BMI, weight loss history, current medications, and overall health profile. Some health conditions and medications may make GLP-1 medications unsuitable. Your provider will walk through eligibility transparently at your You Review.
Your provider may recommend baseline lab work as part of your treatment plan. Lab work is a separate cost from your medication, and your provider will walk through it at your You Review.
Bring a complete picture of your health: current medications, past medications, known allergies, history of any thyroid, pancreatic, gallbladder, or gastrointestinal conditions, pregnancy or family planning, and any previous weight loss medications. The more your provider knows, the better the plan.
The initial You Review is complimentary. Medication costs, and any recommended lab work, are separate and part of your ongoing costs once you begin. Your provider will walk through the full cost picture transparently at your You Review.
OrangeTwist GLP-1 is priced by medication and dose, with no membership required. Membership is the best value: adding TwistUp or TwistUp+ applies your Beauty Bank credit and treatment discount on top. Your provider will walk through exact pricing, including any recommended lab work, at your You Review before anything is agreed.
No. Medical Weight Loss does not require a membership. That said, membership is the best value: adding TwistUp or TwistUp+ gives you Beauty Bank credit plus a discount on treatments, including your GLP-1 medication.
Both Semaglutide and Tirzepatide are given as a once-weekly injection. Most clients self-administer at home, and your provider will walk you through the process during your You Review.
If you’d prefer not to self-administer, in-office injections are available for an additional fee. The injection is subcutaneous (under the skin) and most clients find self-administration straightforward after the first dose.
No. Lab work is a separate cost from your medication. Your provider will confirm whether lab work is recommended for you and walk through the cost at your You Review.
Yes. OrangeTwist offers financing through CareCredit, Alle Cherry, and PatientFi. Ask your provider about options at your You Review.
Most clients begin noticing changes in appetite and eating patterns within the first weeks. Visible weight loss typically begins within the first one to three months. Individual results vary based on starting weight, medication, lifestyle, and clinical profile. Your provider will set realistic expectations at your You Review.
Individual results vary significantly. Clinical trials have shown meaningful average weight loss for both Semaglutide and Tirzepatide over a 12 to 18 month period. Your provider will discuss what to realistically expect for your specific situation.
Talk to your provider about your options, including adjusting your dose or discontinuing treatment. Many clients also use this stage to explore body-contouring or skin-tightening treatments.
Common side effects, particularly in the first weeks, include nausea, mild gastrointestinal upset, constipation or diarrhea, and changes in appetite. These typically ease as your body adjusts and as dosing is calibrated.
GLP-1 medications are not recommended if you are pregnant, breastfeeding, or planning pregnancy, have a personal or family history of medullary thyroid carcinoma, have a history of pancreatitis or certain gastrointestinal conditions, have multiple endocrine neoplasia syndrome type 2, or have other clinical contraindications determined by your provider. Always disclose your full medication and health history at your You Review.
GLP-1 medications have been used clinically for over a decade for type 2 diabetes, and the more recent weight management indications continue to be studied. Your provider will discuss what is currently understood about long-term use as part of your You Review.
Yes. You can stop at any time. Talk to your provider first, particularly around dose tapering.
Contact your OrangeTwist provider immediately. Most early side effects ease with time and dose adjustment, but any concerning symptom should be discussed with your provider.
OrangeTwist providers prescribing GLP-1 medication are trained in medical weight management and supervised by our Medical Advisory Board.
The OrangeTwist Difference
You’re Glowing, We’re Blushing
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Highly Skilled Providers
True experts in their craft, our licensed providers are continuously trained in the latest techniques, treatments, and technologies.
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A Welcoming Experience
Our treatment shops are bright, modern, and welcoming, with a team that’s as approachable as they are skilled.
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A Personalized Touch
No two clients are the same — and we treat them that way. We start every journey with a full You Review so we can understand your unique goals and how to achieve them.
Ready to twist?
Your center team is closer than you think
Every OrangeTwist has its own providers, its own front desk, and its own way of making you feel at home. Pick your nearest center to meet the people who would build your plan and reach out with anything you want to ask before booking. Treatments, pricing, what suits your skin, all of it.
- Meet your providers
- Ask before you book
- Local team, real answers
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